My child had to switch from Medikinet removed to the Zentiva version. Teachers said the generic is hardly working at all.

Can it really be so much different? Both claim to have a 50 % instant-release part.

Medikinet removed has a similar curve as Ritalin LA with a stronger peak between hour 3 and 6. The Zentiva isn’t even documented that well. German article with interesting comparison graphs: https://www.ppt-online.de/heftarchiv/2022/04/individuelle-adhs-therapie-mit-methylphenidat-*removed*praeparaten.html

  • trashcan@sh.itjust.works
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    1 month ago

    My child had to switch from Medikinet removed to the Zentiva version. Teachers said the generic is hardly working at all.

    Unrelated to your question, but please, I need to know what word dot ml decided to filter out lol

  • superduperpirate@lemmy.world
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    1 month ago

    Looks like the post is referring to a Medikinet product that could also be described as delayed release or modified release, instead of the word which was censored in the post. In case anyone else was confused like me.

  • snooggums@lemmy.world
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    1 month ago

    I am on the extended release (ER) for methylphenidate on a high dose for like 20 years and for me it lets me focus while it is working.

    Sustained release (SR) does not work nearly as well for me. Standard release wears off way too fast.

    People have very different rates of success or side effects so yes, it really could be that different! It sounds like this isn’t the right one for your kiddo.

  • Siethron@lemmy.world
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    1 month ago

    Adult on time release generic methylphenidate here. I notice it usually starts working about 45 minutes after ingestion. Instant release only really means as soon as it begins to be digested and everybody’s body is different.

    Also remember, don’t mix it with caffeine or the effects will be greatly reduced.

  • JuBe@lemmy.world
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    27 days ago

    A little bit late to the party, but if you’re in the U.S., you should report this to the FDA’s MedWatch, here. There’s some backstory here, but from personal experience, I can say that the different release mechanisms (e.g., osmotic) can have an impact. It sucks.