Erythritol, a widely used sugar substitute found in many low-carb and sugar-free products, may not be as harmless as once believed. New research from the University of Colorado Boulder reveals that even small amounts of erythritol can harm brain blood vessel cells, promoting constriction, clotting, and inflammation—all of which may raise the risk of stroke.

  • John Richard@lemmy.world
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    9 days ago

    Interesting thing about most sugar substitutes is they actually kill mouth & gut microbiome.

    • testfactor@lemmy.world
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      9 days ago

      That seems like an impressively blanket statement when there’s literally dozens of sugar substitutes that are all wildly chemically different. Insane that all of them would kill your mouth and gut microbiome even when they often work in fundamentally different ways.

      • spicy pancake@lemmy.zip
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        9 days ago

        here’s a pretty good meta-analysis I found of various studies of stevia affecting bacteria in vitro and in vivo

        the conclusion this paper comes to seems to be “depends on the species and strain of bacteria”

          • spicy pancake@lemmy.zip
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            8 days ago

            yes, but I think it warrants further study. some GI issues are related to one or just a few bacterial strains being unbalanced, so it could be extremely useful in treating gut microbiome imbalances to know which strains are negatively impacted by specific sweeteners

            conversely if we found any specific sweetener to have a bacteriostatic or bactericidal effect on a strain that is pathological when overly populated (e.g. H. pylori), that could be a super easy way for some people to prevent chronic flare-ups

      • Fetus@lemmy.world
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        9 days ago

        I also don’t have any studies, but I am aware of xylitol being used in toothpaste, chewing gum, etc., usually with the “assists in the prevention of tooth decay” type of tagline.