• surfrock66@lemmy.world
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    4 days ago

    There’s a lot of snark, but the idea is this only inhibits pain in the peripheries, so it isn’t so psychoactively impacting. You don’t get sedated, the addiction profile is way less, and the LD50 means OD’ing is much harder. I’m sure there’s dependency potential, but it seems this is NOT recreational, which is huge, and if the sedation is less and you can take this and still function, it could be a game changer, allowing people impacted by chronic pain to re-enter the work force and have a better quality of life:

    https://en.wikipedia.org/wiki/Suzetrigine https://pubmed.ncbi.nlm.nih.gov/39775738/

    • surewhynotlem@lemmy.world
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      4 days ago

      For a moment I thought there was a drug called Recreationol. It sounded like a hell of a party.

    • Kyrgizion@lemmy.world
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      4 days ago

      allowing people impacted by chronic pain to re-enter the work force

      You mean they’re just going to force utterly crippled and suffering people to work instead of taking some time to heal in a hospital…

      • surfrock66@lemmy.world
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        4 days ago

        No, lots of people out there years out from an accident or injury can’t work and it leads to the opioid addiction cycle; having an option to control the pain and get people able to either work or do hobbies again, or do things with their families, would be huge.

      • don@lemm.ee
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        4 days ago

        Nowhere in their comment did they even come close to implying what you’re suggesting. There are many folk who’d love to go back to doing the things they love, which includes actual work, but can’t, because the hospital did all they could and sent them on their way to deal with crippling pain on their own. This might let those people go back to doing what they love to do.

        Stop making shit up.

      • catloaf@lemm.ee
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        4 days ago

        There are multiple conditions that cause pain for no apparent physiological reason.

          • blarghly@lemmy.world
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            3 days ago

            Tbf, I don’t think this new drug would do anything about them either, considering it only blocks periferal pain.

  • Guidy@lemmy.world
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    3 days ago

    Hopefully it’s not addictive, so maybe - just fucking maybe - people actually in pain can get it without jumping through a million hoops and being treated like drug-addicted criminals.

    That’d be… neat.

  • captainlezbian@lemmy.world
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    3 days ago

    Even if it had similar addiction profiles to opioids I’d be all for it. Opioid allergies are very common and those of us who have them also deserve to not be in agony after surgeries or physical trauma.

    In fact, I worry that if its nonaddictive it may be pushed onto people who are allergic or nonresponsive to it similar to how nonstimulant adhd meds are. That doesn’t mean I’m not all for nonaddictive painkillers, I’m 100% in favor and if we had a few options that can cover our bases I’d be in favor of shelving the poppy juice into a last resort role, but I hope people don’t lose their sense of nuance in it.

  • Trimatrix@lemmy.world
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    4 days ago

    I will bite. How much? Unless its cheaper than opiates, No one is going to put their profit margin above the common good of society.

      • TheTechnician27@lemmy.world
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        4 days ago

        Alternative: send Vertex Pharmaceuticals’ board to the guillotine and make the medication available for pennies per 50-milligram pill (at cost) or free (publicly funded).

        • huppakee@lemm.ee
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          4 days ago

          Yes that will get people to do research and make new meds available. /s

          • TheTechnician27@lemmy.world
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            4 days ago

            Should I have added “nationalize it and make future research funded and owned by the public”? (A lot of public funding already goes to medical research, but the profits get privatized.)

            Private corporations researching medications so they can price gouge the chronically ill through a copyright-enforced monopoly isn’t the only way to do medical research.

            • huppakee@lemm.ee
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              4 days ago

              The public is definitely not benefitting enough from the research they fund als also the price gouging at the cost of sick people is very problematic, but I’m not in favour of beheading bad people. But I understand that the longer decision makers continue to allow these bad people to do these bad things, the more likely it becomes the guillotine makes an appearance.

    • Mouselemming@sh.itjust.works
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      4 days ago

      I think you (unintentionally) have that backwards. The companies absolutely will and do put their profit margin above the common good.