I had never tried taking it orally, but had to switch due to life circumstances and I swear it’s made a big difference

Has anyone had the opposite experience?

    • Kayday@lemmy.world
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      3 days ago

      Okay, my prescription is a 5mg oral tablet every day. This article is talking about 200+ mg orally to be effective, or 100mg rectally. Why in the world would my prescription be so low??
      Also:

      Administration of oral micronized progesterone capsules rectally instead of orally likewise may be effective and may achieve much higher progesterone levels than oral administration. However, rectal administration of oral progesterone capsules has not been formally studied.

      Am I wasting money having 5mg per day orally? Would have been nice to know 6 months ago when I started.

      • dandelion (she/her)@lemmy.blahaj.zone
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        3 days ago

        are you taking bioidentical, micronized progesterone? It sounds like you might be taking a synthetic progestin, which is different…

        I have a link to a resource on the differences if I remember to come back, I’m AFK right now so I don’t have it, sorry

          • dandelion (she/her)@lemmy.blahaj.zone
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            3 days ago

            yep, that’s Medroxyprogesterone (MP), a synthetic progestin, which is not progesterone.

            I recommend switching to micronized, bioidentical progesterone, which is safer (has fewer side effects and long term risks).

            Taking MP is not the end of the world like some in the community think (there is a lot of fear about it because it increases risks of cancers, etc.), but it’s definitely not ideal and does carry risks. Plenty of people do experience side effects like mood problems and depression from taking it.

            Also, while it’s not the same as having progesterone (the hormone you would have if you were a cis woman), it does have some anti-androgen effects which might be helpful for feminizing.